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CLINICAL SPECIALTY

Anti-Aging & Regenerative

Anti-aging and regenerative care at Le.J Plastic Surgery in Seoul: injectable skin treatments, ReCell regenerative therapy and hyperbaric oxygen therapy.

Anti-Aging & Regenerative

Anti-Aging & Regenerative Care in Seoul at Le.J Plastic Surgery

Woman with dark hair facing the camera against a light background.

Medically reviewed by Dr. Kim Ji Sun, M.D., M.S., Ph.D., Board-Certified Otolaryngologist · Le.J Plastic Surgery, Gangnam-gu, Seoul

Anti-aging and regenerative care covers treatments aimed at the visible signs of skin ageing — fine lines, reduced elasticity, uneven texture and loss of firmness — together with treatments intended to support tissue repair. At Le.J Plastic Surgery in Gangnam, Seoul, the category holds seven distinct treatments, and they do not all belong to the same kind of medicine: five are injectable skin treatments, one is a cell-harvesting technology, and one is a physician-supervised medical therapy delivered in a pressurised chamber. All are assessed and performed by Dr. Kim Ji Sun, a board-certified otolaryngologist with 20 years of experience and more than 4,000 clinical cases.

What Is Anti-Aging & Regenerative Care?

Anti-aging and regenerative care is the category of treatments that aim to improve skin quality and support the skin's own repair processes, rather than to reposition tissue surgically.

  • It addresses fine lines, wrinkles, reduced elasticity, uneven texture and loss of skin firmness.

  • Most of the treatments in this category are injectable, and several work by stimulating the skin's own collagen production rather than by adding volume directly.

  • Treatments in this category do not stop natural ageing and do not guarantee permanent results.

  • Results may appear immediately or develop over weeks to months, depending on which treatment is used.

  • Which treatment is appropriate depends on whether the primary concern is texture, hydration, fine lines, firmness or volume loss — these are different problems with different answers.

Two parts of this category sit apart from the rest, and this page keeps them apart rather than folding them in. Hyperbaric oxygen therapy is a medical treatment with recognised clinical indications; at this clinic it is part of the postoperative recovery facilities. ReCell is a cell-harvesting technology whose intended use depends on the device model and the applicable medical indication. Neither is described here as an anti-ageing treatment, because the clinic's own documentation does not describe them that way.

Who Performs Anti-Aging & Regenerative Care at Le.J Plastic Surgery

Dr. Kim Ji Sun, Founder and Medical Director at Le.J Plastic Surgery.
Dr. Kim Ji Sun, M.D., M.S., Ph.D.
Board-certified Otorhinolaryngologist

Every treatment in this category at Le.J Plastic Surgery is assessed and performed personally by Dr. Kim Ji Sun, the clinic's founder and Medical Director.

Dr. Kim is a board-certified otolaryngologist who earned an M.D., a Master's degree and a Ph.D. from Dankook University College of Medicine, completed internship and residency at Dankook University Hospital, trained as a Clinical Fellow in the Department of Otorhinolaryngology at Asan Medical Center, and has served as a Guest Professor at Stanford University School of Medicine in the United States.

Stem cell therapy is listed among Dr. Kim's core specialisations, alongside rhinoplasty, forehead lift surgery and fat grafting. Hyperbaric oxygen therapy for post-operative recovery appears separately, under subspecialty technique expertise — which is consistent with how the clinic positions its hyperbaric equipment, as part of an integrated postoperative recovery system rather than as a stand-alone aesthetic service.

Le.J Plastic Surgery is a single-doctor clinic, so the surgeon who assesses you is the surgeon who treats you.

Anti-Aging & Regenerative Care Options / Types Available

Seven treatments sit in this category. The first five are injectables and differ mainly in what they are made of; the last two are not injectables at all.

Treatment

What it is

Session time

Radiesse®

Calcium hydroxylapatite microspheres in a carboxymethylcellulose gel carrier

Approximately 15–45 minutes

Rejuran®

Polynucleotides derived from purified salmon DNA

Approximately 20–40 minutes

Juvelook®

Poly-D,L-lactic acid combined with hyaluronic acid

Approximately 30–60 minutes

Elravie Re2O®

Processed human acellular dermal matrix containing collagen and elastin

Approximately 30–60 minutes

HiloWave®

A dual hyaluronic acid formulation, high- and low-molecular-weight

Approximately 15–30 minutes for the injection itself

ReCell Regenerative Therapy

A device that processes a small sample of the patient's own skin into a cell suspension

Depends on sampling, processing and application

Hyperbaric Oxygen Therapy (HBOT)

Medical-grade oxygen breathed inside a pressurised chamber

Approximately 90–120 minutes at treatment pressure

The five injectables are not interchangeable. Radiesse® works in two stages — the gel carrier provides initial volume while the calcium hydroxylapatite stimulates collagen production. Rejuran® and Juvelook® target skin quality rather than volume, the first with polynucleotides and the second with poly-D,L-lactic acid alongside hyaluronic acid. Elravie Re2O® is made from processed donated human dermal tissue and is intended for texture, pores and elasticity. HiloWave® is hyaluronic-acid based and aimed at hydration and skin quality, and the clinic is explicit that it is not a substitute for surgical lifting or for a conventional volumising filler when substantial structural correction is required.

The American Society of Plastic Surgeons describes calcium hydroxylapatite within the injectable category as producing a natural result that does not migrate, with rare side effects.

ReCell Regenerative Therapy uses the RECELL Autologous Cell Harvesting Device together with single-use processing components and skin-sampling instruments. The clinic's description is specific and limited: the device can process a small skin sample into a cell suspension for application to specific treatment areas, and the intended use depends on the device model and the applicable medical indication. Its stated benefit is support for skin repair, and a possible reduction in the amount of donor skin required in certain procedures.

Hyperbaric Oxygen Therapy (HBOT) is a medical treatment in which the patient breathes medical-grade oxygen inside a pressurised chamber, increasing the amount of oxygen dissolved in the blood and reaching tissues. Its clinically established uses are specific conditions — decompression sickness, carbon monoxide poisoning, certain problem wounds, radiation tissue injury, refractory osteomyelitis, and compromised grafts or flaps among them. The clinic's own guidance states that it should not automatically be described as a combination treatment for wellness, anti-ageing or cosmetic purposes, and this page follows that.

Who Is a Good Candidate for Anti-Aging & Regenerative Care?

Woman examining her neck in a mirror.

Suitable candidates:

  • Adults concerned about visible skin ageing — fine lines, wrinkles, reduced firmness or uneven texture — who have realistic expectations and are medically suitable for the recommended treatment.

  • For the volume-oriented injectables: adults seeking restoration of age-related volume loss or improvement in selected facial contours.

  • For the skin-quality injectables: adults whose concern is texture, hydration, visible pores or dull-looking skin rather than reshaping.

  • For HBOT: patients with a medical condition for which hyperbaric oxygen has an accepted indication, who have been evaluated by a qualified physician.

Who should postpone or be assessed further:

  • Anyone with an active skin infection or inflammation at the planned injection site.

  • Anyone with a known allergy or hypersensitivity to a product's ingredients.

  • Patients who are pregnant or breastfeeding, and patients with bleeding disorders or taking medicines that affect clotting.

  • Patients with a history of abnormal scarring or immune-related conditions, for the dermal-matrix and biostimulatory injectables in particular.

  • For HBOT specifically: patients with untreated pneumothorax, significant difficulty equalising ear pressure, certain lung conditions, or medications and conditions that may increase oxygen-toxicity or seizure risk. The clinic is explicit that this is determined by medical screening and not by a fixed public checklist.

There is one point that belongs in a candidacy section rather than buried further down. Regulatory status for cell-based and regenerative products differs by country, and the U.S. Food and Drug Administration advises patients considering any regenerative medicine therapy to establish, before treatment, whether the specific product is approved or is being studied under an investigational plan — and states plainly that a product being made from a patient's own cells does not by itself remove the need for that review. That is guidance about the category under U.S. law, not a statement about any treatment offered here; Le.J Plastic Surgery has not published approval, licensing or registration information for the products in this category, so none is claimed on this page. It is a reasonable question to put to the clinic directly.

What to Expect: Procedure, Recovery, and Results Timeline

Medical illustration of a DNA double helix.

The consultation reviews your medical history, examines your skin condition and the signs of ageing, identifies your treatment goals and assesses suitability for the available options. Expected outcomes, limitations, potential risks, alternatives and the proposed plan are explained before anything is agreed.

For the injectable treatments the sequence is broadly the same: the treatment area is cleansed, a topical numbing product is applied where appropriate, the product is administered into the planned skin layer, the area is checked, and aftercare instructions follow. Many non-surgical treatments in this category require no anaesthesia at all; where comfort measures are used, they are usually topical numbing cream, local anaesthesia or cooling.

Treatment

Recovery

When results appear

Radiesse®

Many resume normal activities soon after; swelling or bruising may last several days

Initial volume soon after; collagen-related change over following weeks and months

Rejuran®

Normal activities shortly after; injection-site bumps for hours to a few days

Gradually over several weeks; a course of sessions may be recommended

Juvelook®

Redness, swelling or tenderness improving within a few days to a week

Gradually over several weeks to months

Elravie Re2O®

Light activity shortly after; mild effects improving over several days

Over the following days to weeks

HiloWave®

Routine activities the same or next day; marks may persist several days

Hydration early; overall skin quality over following weeks

ReCell

Depends on the treated area and the size and depth of the skin defect; healing may take weeks or longer

Depends on the indication and healing process

HBOT

No surgical recovery period; patients usually leave after assessment

Depends on the underlying diagnosis, often over a series of sessions

Planning a trip around this category is less predictable than around a single operation, and the clinic says so rather than giving a number: the required stay depends on the selected treatment, recovery needs and the follow-up schedule. Some non-surgical procedures can be completed in a short visit; treatments requiring multiple sessions or monitoring need longer. HBOT in particular is often delivered as a series — some recognised indications involve daily treatment for roughly four to eight weeks.

Side effects across the injectable treatments are broadly similar: redness, swelling, tenderness, bruising, irritation, small injection-site bumps and temporary discomfort. The less common but more serious possibilities include infection, persistent nodules, prolonged inflammation, allergic or immune reactions, and injection-related vascular complications. Accidental injection into a blood vessel can cause tissue damage and, rarely, vision complications, which is why any visual disturbance after a facial injection is an emergency rather than something to monitor at home. Urgent medical care is also warranted for severe or increasing pain, pale or mottled skin, or unusual discoloration after injection.

ReCell carries its own profile — pain, infection, delayed healing, scarring, pigmentation changes and complications at the skin-sampling site. HBOT's risks are different again: ear or sinus barotrauma, temporary vision changes, oxygen toxicity and, rarely, oxygen-toxicity seizures, alongside a significant fire-safety consideration inherent to an oxygen-rich environment. The U.S. regulator's letter to health care providers on hyperbaric device safety addresses that last point directly for the category, and its recommendations include hyperbaric-compatible clothing such as cotton, since some fabrics produce more static electricity than others.

Aftercare for the injectables follows a common pattern: gentle skincare and sun protection, no rubbing or unnecessary pressure on treated areas, and a temporary pause on strenuous exercise, saunas, excessive heat and exfoliating treatments where the clinician advises it.

Combining Anti-Aging & Regenerative Care with Other Treatments

Treatment plans in this category may combine skincare, energy-based procedures and injectable treatments; the clinic's position is that the appropriate combination, order and timing are determined by the clinician on the basis of safety and treatment goals rather than chosen from a menu. Radiesse® may be combined with hyaluronic acid fillers or selected skin-rejuvenation procedures. Rejuran®, Juvelook® and Elravie Re2O® may each be considered alongside other treatments where clinically appropriate, with sequence and spacing set to limit irritation. HiloWave® may be considered alongside a skincare plan or selected aesthetic treatments on the same basis.

Two limits, stated rather than glossed. HBOT may be combined with condition-specific medical treatment — wound care, surgery, antibiotics — when clinically indicated, and the clinic's documentation states directly that it should not automatically be described as a combination treatment for wellness, anti-ageing or cosmetic purposes. And the clinic has not confirmed combination protocols for ReCell. The clinic publishes no per-procedure pages for these, so they are listed without links rather than linked to pages that do not exist.

Patients also ask how this category relates to the clinic's other work. The nearest neighbours are facial lifting and contouring, where the concern is sagging and definition rather than skin quality, and the clinic's skin care treatments. Which category your concern belongs to is itself a consultation question, and the answer is not always the one patients arrive with.

Safety, Precision, and Clinic Standards

Waiting area at Le.J Plastic Surgery with white seating and a Christmas tree.

Le.J Plastic Surgery is a Registered Medical Institution for Attracting Foreign Patients, certified by the Ministry of Health and Welfare in compliance with the Medical Overseas Expansion and Foreign Patients Attraction Act. This is a registration for treating international patients; it is not an accreditation of any treatment in this category.

The clinic's stated quality process centres on individual assessment before treatment, diagnostic imaging where appropriate, technique selection matched to the patient rather than to a standard protocol, and postoperative monitoring. Its recovery facilities include hyperbaric oxygen equipment, which the clinic presents as part of integrated postoperative recovery care.

For the injectable treatments, the controls that matter are sterile single-use equipment, accurate assessment of the treatment area, and informed consent covering the specific product. The clinic's documentation for several of these products states that technique and permitted use must follow the official product instructions and local requirements — which is where the real safety constraint sits for an injectable, rather than in anything visible to the patient on the day.

Le.J Plastic Surgery publishes neither case volumes nor complication rates for this specialty, and this page claims neither. It has also not published a risk-reduction protocol specific to it, nor clinic-specific technique details for most of these treatments. Both are fair questions at consultation.

The Bottom Line

  • Anti-aging and regenerative care at Le.J Plastic Surgery is seven treatments: five injectables, one cell-harvesting technology, and one physician-supervised medical therapy.

  • The five injectables differ by what they are made of and what they target — volume, collagen stimulation, texture, hydration — and they are not substitutes for one another.

  • Hyperbaric oxygen therapy and ReCell are medical treatments with their own indications; the clinic does not present either as an anti-ageing treatment and neither does this page.

  • All seven are assessed and performed by Dr. Kim Ji Sun, a board-certified otolaryngologist with 20 years of experience and 4,000+ clinical cases.

  • Nothing here stops ageing, and the clinic gives no single figure for how long results last, because none applies across seven different treatments.

Frequently Asked Questions

Which of these treatments do I actually need? That depends on what your main concern is, and the categories are genuinely different. Volume loss and slackening contours point towards the collagen-stimulating and volumising injectables; rough texture, visible pores or dullness point towards the skin-quality injectables; hydration is a third problem again. The consultation exists to sort this out, and the answer is sometimes that a treatment in a different category — lifting, or skin care — is the better fit.

How long should I plan to stay in Korea? The clinic does not give a single figure, and that is honest rather than evasive. Some non-surgical treatments in this category can be done in a short visit; others are given as a course of sessions, which lengthens the stay considerably. HBOT, where it is indicated, commonly runs daily for several weeks. Ask for a schedule for your specific plan before booking flights.

Will the injections hurt? Expect warmth, tingling, stinging, pressure or temporary tenderness rather than sharp pain. Topical numbing cream is commonly used for the injectable treatments, and several of them can be tolerated without it. Intensity varies with the treatment area and individual sensitivity.

How long do the results last? There is no single answer across seven treatments. The injectables are not permanent, and maintenance sessions may be recommended. For the collagen-stimulating products, change develops over weeks and months rather than appearing on the day, and how long it holds varies with the treatment area, the formulation, the dose and individual response.

Is hyperbaric oxygen therapy an anti-ageing treatment? No, and the clinic's own documentation says so. HBOT is a medical treatment for recognised indications, delivered under physician supervision with the pressure, session length and frequency set according to the underlying condition. At this clinic it also appears as part of postoperative recovery care. It is listed in this category, but it is not offered as a cosmetic treatment and should not be understood as one.

What is ReCell, in plain terms? It is a device-based technique that takes a small sample of your own skin and processes it into a cell suspension that can be applied to a specific treatment area. Its intended use depends on the device model and the applicable medical indication, and the clinic's stated benefit is support for skin repair rather than rejuvenation. Whether it is appropriate for a particular problem is a diagnosis question, answered at consultation.

What should I tell the clinic before treatment? Your medical history, allergies, all medications and supplements, previous cosmetic treatments and injectables, any current skin concerns, and whether you are pregnant or breastfeeding. Follow the clinic's instructions on sun exposure and skincare beforehand, and do not stop any prescribed medication without medical advice.

Book a Consultation at Le.J Plastic Surgery

Anti-aging and regenerative care at Le.J Plastic Surgery in Gangnam, Seoul begins with an assessment of your skin and a conversation about what you actually want changed — which, in this category more than most, determines whether an injectable, a different category of treatment, or nothing at all is the right answer. Consultations run Monday to Friday, 10:00–19:00 KST, and Saturday from 10:00 KST. International enquiries are handled by the clinic's counseling manager, Park Somi, and English-language support is available. If you are travelling from abroad, ask for the session schedule for your specific plan before you book, since several of these treatments are given as a course rather than once. You can use the clinic's contact page, by phone at +82-2-516-7153 or by email at info@lejplasticsurgery.com.

Disclaimer

This page is for general information only and is not medical advice. Individual results vary and cannot be guaranteed. Suitability for any procedure can only be determined through an in-person medical consultation with a qualified doctor.

Sources & Further Reading

  • U.S. Food and Drug Administration — Important Patient and Consumer Information About Regenerative Medicine Therapies

  • U.S. Food and Drug Administration — Follow Instructions for Safe Use of Hyperbaric Oxygen Therapy Devices (Letter to Health Care Providers)

  • American Society of Plastic Surgeons — Types of Dermal Fillers

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