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CLINICAL PROCEDURE GUIDE
Elravie Re2O®
Elravie Re2O® at Le.J Plastic Surgery in Gangnam, Seoul is an injectable treatment made from processed human acellular dermal matrix, used to improve skin quality and texture.
Elravie Re2O® in Seoul at Le.J Plastic Surgery

Medically reviewed by Dr. Kim Ji Sun, M.D., M.S., Ph.D., Board-Certified Otolaryngologist · Le.J Plastic Surgery, Gangnam-gu, Seoul
Elravie Re2O® is an injectable skin treatment made from processed human acellular dermal matrix (hADM), derived from donated human skin tissue, and intended to improve skin quality and texture. That source material sets it apart from every other injectable on this site and raises questions no other one raises, so this page addresses them directly rather than in passing. At Le.J Plastic Surgery in Gangnam-gu, Seoul it sits within the clinic's Anti-Aging & Regenerative range, and it is performed personally by Dr. Kim Ji Sun, the clinic's founder and Medical Director and the listed performing doctor for the parent Anti-Aging & Regenerative specialty.
What Is Elravie Re2O®?
Elravie Re2O® is the injection of a processed human acellular dermal matrix product into a planned layer of the skin, intended to improve skin quality and texture.
The material is processed human acellular dermal matrix (hADM), derived from donated human skin tissue.
It contains extracellular matrix (ECM) components, including collagen and elastin, that support skin structure.
"Acellular" means the cells have been removed during processing; what remains is the structural matrix.
It is administered into a planned skin layer using an appropriate injection technique, after the area is cleansed and prepared.
The stated purpose is improvement in skin quality and texture — not contouring, and not volume restoration.
The source material is the thing to understand first. This is not a synthetic polymer, not a hyaluronic acid product, and not material taken from your own body. It is derived from donated human tissue, processed to remove the cells. A patient for whom that origin is a consideration — on medical, religious or personal grounds — should know it before the consultation rather than during it, which is why it leads this page.
The clinic has not published technique details specific to its own protocol, and this page does not supply any in their place. It has likewise not confirmed approved claims of its own for this treatment, so nothing beyond the stated purpose above is asserted here — not an efficacy figure, not a comparison, and not a regulatory status.
Who Performs Elravie Re2O® at Le.J Plastic Surgery

Dr. Kim Ji Sun, M.D., M.S., Ph.D.
Board-certified Otorhinolaryngologist
Elravie Re2O® is performed personally by Dr. Kim Ji Sun, the clinic's founder and Medical Director and the listed performing doctor for the parent Anti-Aging & Regenerative specialty.
Dr. Kim is a board-certified otolaryngologist who earned an M.D., a Master's degree and a Ph.D. from Dankook University College of Medicine, completed internship and residency at Dankook University Hospital, trained as a Clinical Fellow in the Department of Otorhinolaryngology at Asan Medical Center, and has served as a Guest Professor at Stanford University School of Medicine in the United States.
Dr. Kim's most recent relevant academic activity is a 2026 lecture on non-surgical facial rejuvenation and closed rhinoplasty at the 12th meeting of the Korean Academy of Facial Plastic and Reconstructive Surgery, where Dr. Kim is a regular member and serves on the academic, public-relations and international committees.
Le.J Plastic Surgery is a single-doctor clinic, so the surgeon who assesses you is the surgeon who treats you.
Who Is a Good Candidate for Elravie Re2O®?
Suitable candidates:
Adults concerned about uneven skin texture, visible pores, fine lines, or reduced skin elasticity, who have been assessed as suitable by a qualified medical professional.
Patients comfortable with a treatment derived from donated human tissue, having been told that is what it is.
Who should avoid, postpone, or be assessed individually:
People with active skin infections or inflammation at the treatment site.
People with known relevant allergies, or certain medical conditions.
Patients with a history of abnormal scarring, immune-related conditions, or other significant medical concerns, who should receive an individualised assessment.
That third group is listed separately for a reason. Where a treatment introduces a structural matrix into the skin, a history of abnormal scarring or an immune-related condition is not a routine checkbox but the substance of the assessment. The consultation accordingly reviews skin concerns, medical history, allergies, medications, previous aesthetic treatments and desired outcomes, examines the skin, and discusses whether Re2O is appropriate at all — alongside alternatives, expected results, risks and aftercare.
Patients enquiring from the United States often want to compare this treatment with what is available at home before committing to a trip. The honest framing is that the comparison is not product-against-product on a page; it is a clinical question about which approach suits the skin in front of the examiner, and it is reasonable to ask for it to be answered that way.
What to Expect: Procedure, Recovery, and Results Timeline

At consultation the provider reviews your skin concerns, medical history, allergies, medications, previous aesthetic treatments and desired outcomes, examines the skin, and explains alternatives, expected results, risks and aftercare.
On the day, the treatment area is cleansed and topical numbing cream may be applied. The prepared product is administered into the planned skin layer using an appropriate injection technique. The provider then checks the treated area and explains aftercare instructions.
Stage | What the clinic states |
|---|---|
Appointment length | Approximately 30–60 minutes, depending on the treatment area and clinical protocol |
Anaesthesia | Topical numbing cream may be used; stinging, pressure or brief pain may occur during injection |
Early recovery | Mild redness, swelling, tenderness or bruising, typically improving over several days |
Return to activity | Most patients resume light daily activities shortly after treatment |
When results appear | Initial changes over the following days to weeks |
Final result | Generally apparent over several weeks |
Possible side effects include redness, swelling, tenderness, bruising, injection-site bumps, and discomfort. Less common but potentially serious complications include infection, persistent inflammation, allergic or immune reactions, scarring, and tissue injury.
Aftercare follows the clinician's instructions for cleaning and caring for the treated area. Avoid rubbing, massaging, or applying pressure to the area unless advised by the clinician, and follow the guidance given on exercise, heat exposure and skincare. Seek medical attention if severe pain, unusual skin changes, or signs of infection develop.
For international patients, the clinic advises planning a stay of approximately 1–2 days in Korea, including the treatment appointment and any necessary follow-up, and you may be able to fly home within that period provided you feel well and your treating clinician confirms it is safe to travel. The result, though, arrives after you are home: initial changes over days to weeks, the final picture over several weeks. If something feels wrong after returning home, patients can reach the clinic's English-speaking counselling manager by phone or email.
Combining Elravie Re2O® with Other Treatments
Other skin-quality injectables in the same range — the clinic offers further injectable options aimed at skin texture and quality, each working through a different material.
Volumising injectables — where the concern is facial volume loss rather than skin quality, Radiesse addresses a different problem.
Device-based and laser skin treatments — also available at the clinic, and sometimes the better match for the concern.
The clinic publishes no per-procedure pages for several of these, so they are listed without links rather than linked to pages that do not exist. Elravie Re2O® may be considered alongside other aesthetic treatments only when clinically appropriate, and the clinician should determine compatibility, treatment order, and suitable intervals based on the product instructions and patient assessment. The clinic has not published alternatives or comparisons of its own for this treatment, so none are ranked here.
Safety, Precision, and Clinic Standards
Le.J Plastic Surgery is a Registered Medical Institution for Attracting Foreign Patients, certified by the Ministry of Health and Welfare in compliance with the Medical Overseas Expansion and Foreign Patients Attraction Act. This is a registration for treating international patients; it is not an accreditation of any treatment in this category.
The clinic has not published a risk-reduction protocol specific to this procedure, and that gap is recorded here rather than filled with inference.
Because the material is derived from donated human tissue, the relevant category context is the one that governs tissue products rather than the one that governs synthetic injectables. The U.S. Food and Drug Administration states in its consumer information on tissue and tissue products that the overall risk of disease transmission through tissue transplantation is believed to be very low, and describes the safeguards behind that: reviewing the donor's medical history, physically assessing the donor, and testing for diseases that could pass to recipients. Donor testing has been required since 1993. That is a statement about how the category is handled in general, not about any particular product, and it is included because a patient told that a treatment comes from donated tissue deserves to know that screening regimes for such material exist and what they consist of. What material is used, where it was processed, and under which country's requirements are then fair and specific questions to put to the clinic.
Le.J Plastic Surgery publishes neither case volumes nor complication rates for this procedure, and this page claims neither. That is a fair question at consultation, as is the one worth asking any surgeon in this category: how many of these operations they have performed, how many involved complications, and what follow-up to expect if something goes wrong.
The Bottom Line
Elravie Re2O® is made from processed human acellular dermal matrix derived from donated human skin tissue, containing collagen and elastin among its ECM components.
The stated purpose is improvement in skin quality and texture — not contour, not volume.
The appointment takes approximately 30–60 minutes; initial changes appear over days to weeks, the final picture over several weeks.
Abnormal scarring history, immune-related conditions and relevant allergies call for individual assessment rather than a standard yes or no.
Redness, swelling, tenderness and bruising are the common effects; infection, persistent inflammation, immune reactions, scarring and tissue injury are the serious ones.
The clinic has not confirmed a risk-reduction protocol, alternatives, or approved claims of its own for this treatment, and none are supplied here.
Frequently Asked Questions
Where does the material come from? It is processed human acellular dermal matrix — derived from donated human skin tissue, with the cells removed during processing, leaving extracellular matrix components including collagen and elastin. It is not synthetic, and it is not taken from your own body. If the origin of the material matters to you, raise it at consultation; it is a reasonable thing to ask about in detail.
Is tissue-derived material screened? For the category generally, yes. The FDA states that the overall risk of disease transmission through tissue transplantation is believed to be very low, and describes donor medical-history review, physical assessment of the donor, and disease testing as the safeguards, with donor testing required since 1993. What applies to the specific product used here, and under which country's requirements, is a question to put to the clinic directly.
What is it meant to improve? Skin quality and texture: uneven texture, visible pores, fine lines, and reduced elasticity are the listed concerns. Potential benefits include smoother-looking skin texture, improved appearance of fine lines, and changes in firmness or elasticity. Results vary by individual, and outcomes are not guaranteed.
Does it hurt? Treatment may cause mild to moderate discomfort, stinging, or tenderness during administration. Topical numbing cream may be used to reduce discomfort, and the level of discomfort varies with the treatment area and individual sensitivity.
How long should I stay in Korea, and when can I fly? Plan approximately 1–2 days, including the appointment and any necessary follow-up. You may be able to fly home within that period provided you feel well and your treating clinician confirms it is safe to travel.
Who should not have this treatment? People with active skin infections or inflammation at the treatment site, known relevant allergies, or certain medical conditions may need to avoid or postpone it. A history of abnormal scarring, immune-related conditions, or other significant medical concerns calls for an individualised assessment rather than a general rule.
What should I do if something looks wrong after I get home? Seek medical attention locally for severe pain, unusual skin changes, or signs of infection — spreading redness, fever, or unusual discharge — rather than waiting for a scheduled follow-up. Contact the clinic as well; English-language support is available by phone and email.
How should I prepare? Have a medical consultation reviewing your medical history, allergies, current medications, and previous aesthetic procedures. Follow the clinic's instructions on skincare and preparation, avoid irritating skincare products on the treatment area and alcohol if advised, and do not stop prescribed medications without medical advice.
Book a Consultation at Le.J Plastic Surgery

Elravie Re2O® is offered at Le.J Plastic Surgery in Gangnam-gu, Seoul by Dr. Kim Ji Sun, within the clinic's Anti-Aging & Regenerative range. Because the material is tissue-derived and the suitability assessment turns on medical history as much as on skin condition, the consultation is where the decision is actually made. Consultations run Monday to Friday, 10:00–19:00 KST, and Saturday from 10:00 KST. International enquiries are handled by the clinic's counseling manager, Park Somi, and English-language support is available. You can use the clinic's contact page, by phone on +82-2-516-7153, or by email at info@lejplasticsurgery.com.
Disclaimer
This page is for general information only and is not medical advice. Individual results vary and cannot be guaranteed. Suitability for any procedure can only be determined through an in-person medical consultation with a qualified doctor.
Sources & Further Reading
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