Rejuran®

Rejuran® in Seoul at Le.J Plastic Surgery

Medically reviewed by Dr. Kim Ji Sun, M.D., M.S., Ph.D., Board-Certified Otolaryngologist · Le.J Plastic Surgery, Gangnam-gu, Seoul

Rejuran® is an injectable skin treatment commonly formulated with polynucleotides (PN) derived from purified salmon DNA, used to support skin quality, hydration, elasticity, and the appearance of fine lines. It is a skin-quality treatment rather than a contouring one: the target is texture and condition, not shape or volume. At Le.J Plastic Surgery in Gangnam-gu, Seoul it sits within the clinic's Anti-Aging & Regenerative range, and it is performed personally by Dr. Kim Ji Sun, the clinic's founder and Medical Director and the listed performing doctor for the parent Anti-Aging & Regenerative specialty.

What Is Rejuran®?

Rejuran® is a course of small injections placed into selected areas of the skin, delivering a polynucleotide-based material intended to support skin quality rather than to add contour.

• The active material is polynucleotides (PN) derived from purified salmon DNA.

• It is delivered by multiple small injections into selected areas, not as a single placement.

• The stated targets are skin texture, hydration, elasticity and the appearance of fine lines.

• Improvements are described as developing gradually over several weeks, and a course of sessions may be recommended depending on the product and treatment goals.

• A session commonly takes approximately 20–40 minutes, excluding consultation and numbing time.

This is where the distinction worth holding onto sits. A volumising injectable is judged by whether a hollow has been filled; this one is judged by how the skin itself looks and behaves weeks later. The two are easy to confuse at a consultation because both arrive by needle, and a patient expecting one while being offered the other will find the result disappointing for reasons that have nothing to do with how well the treatment was performed.

The clinic's own stated position on what it can do is narrow, and that is deliberate. Rejuran is an injectable polynucleotide-based treatment used to support skin quality and improve the appearance of texture and fine lines. It may help improve selected skin concerns, depending on the product formulation and individual response. Results vary, multiple sessions may be required, and treatment does not guarantee permanent improvement or replace other treatments when clinically indicated. The clinic has not published technique details specific to its own protocol, and this page does not supply any in their place.

Who Performs Rejuran® at Le.J Plastic Surgery

Dr. Kim Ji Sun, M.D., M.S., Ph.D.
Board-certified Otorhinolaryngologist

Rejuran® is performed personally by Dr. Kim Ji Sun, the clinic's founder and Medical Director and the listed performing doctor for the parent Anti-Aging & Regenerative specialty.

Dr. Kim is a board-certified otolaryngologist who earned an M.D., a Master's degree and a Ph.D. from Dankook University College of Medicine, completed internship and residency at Dankook University Hospital, trained as a Clinical Fellow in the Department of Otorhinolaryngology at Asan Medical Center, and has served as a Guest Professor at Stanford University School of Medicine in the United States.

Dr. Kim's most recent relevant academic activity is a 2026 lecture on non-surgical facial rejuvenation and closed rhinoplasty at the 12th meeting of the Korean Academy of Facial Plastic and Reconstructive Surgery, where Dr. Kim is a regular member and serves on the academic, public-relations and international committees.

Le.J Plastic Surgery is a single-doctor clinic, so the surgeon who assesses you is the surgeon who treats you.

Who Is a Good Candidate for Rejuran®?

Suitable candidates:

• Adults seeking improvements in skin texture, elasticity, and overall skin appearance.

• Patients whose concern is skin condition — uneven texture, visible pores, fine lines, dull-looking skin — rather than structural laxity or lost volume.

• Patients comfortable with a course of sessions and a gradual change rather than an immediate one.

Who should avoid or postpone:

• People with known allergies to product ingredients, or an active skin infection at the injection sites.

• Patients who are pregnant or breastfeeding, who have a bleeding disorder, or who take medication affecting bleeding — all require medical review before treatment.

• Patients with other medical conditions that the consultation identifies as relevant.

Suitability depends on skin condition, medical history, treatment goals, and professional assessment, and the consultation exists to settle all four rather than to confirm a decision already made. A qualified medical professional reviews skin concerns, medical history, allergies, medications and previous cosmetic treatments, assesses suitability, discusses realistic outcomes and risks, and determines whether treatment is appropriate at all.

Patients enquiring from the United States usually arrive with a specific concern already named — texture, pores, the skin under the eyes — and the useful thing to establish early is whether that named concern is one this treatment addresses. The American Academy of Dermatology recommends that before undergoing any cosmetic procedure consumers ask what the risks for the procedure are, and ask the doctor how many times they have performed the exact procedure — a sound list to work through wherever the consultation happens.

What to Expect: Procedure, Recovery, and Results Timeline

At consultation a qualified medical professional reviews your skin concerns, medical history, allergies, medications and previous cosmetic treatments, assesses suitability, and explains realistic outcomes and risks.

On the day, the skin is cleansed and prepared, a topical numbing product may be applied, and small injections are administered into the selected areas. The skin is then assessed and post-treatment care instructions are given.

Stage	What the clinic states
Session length	Approximately 20–40 minutes, excluding consultation and numbing time
Anaesthesia	Topical numbing cream is commonly used; pain levels vary by individual and treatment area
Immediate effects	Small injection-site bumps, redness or swelling for several hours to a few days
Return to activity	Many patients return to normal activities shortly after treatment
When results appear	Gradually over several weeks
Course	A course of sessions may be recommended depending on the product and treatment goals

Rejuran involves multiple injections, so temporary stinging, pinching or discomfort is common, and the level varies by individual and treatment area. Temporary redness, swelling, small injection-site bumps, bruising, tenderness and itching may occur. Less common but more serious complications can include infection, persistent inflammation, allergic reactions, or other injection-related problems.

Aftercare follows the clinic's instructions on cleansing, skincare, makeup and sun protection; avoid rubbing or applying unnecessary pressure to treated areas initially. The clinician may also recommend temporarily avoiding strenuous exercise, saunas, and excessive heat.

For an international patient the logistics are comparatively simple, which is itself worth saying given how often they are not. A short stay is generally sufficient for an outpatient session, with extra time allowed if a follow-up appointment is recommended or if bruising and swelling need assessment. Patients can generally fly once they feel comfortable and any immediate swelling or discomfort is manageable, and travel timing should be confirmed with the treating clinic, especially if follow-up is needed. The one thing a short trip cannot accommodate is a full course: if several sessions are planned, the schedule rather than the single appointment is what the travel has to be built around. If something feels wrong after returning home, patients can reach the clinic's English-speaking counselling manager by phone or email.

Combining Rejuran® with Other Treatments

• Other skin-quality injectables in the same range — the clinic offers further injectable options aimed at skin texture and quality, each working through a different material.

• Volumising injectables — where the concern is lost facial volume rather than skin condition, Radiesse addresses a different problem entirely.

• Device-based skin treatments — selected laser and energy-based options are also available at the clinic.

The clinic publishes no per-procedure pages for several of these, so they are listed without links rather than linked to pages that do not exist.

Rejuran may be combined with selected skin-rejuvenation treatments when clinically appropriate. The sequence and timing should be determined by the clinician to limit irritation and other complications — which is the substantive point rather than a formality, since stacking treatments that each irritate the skin is how an otherwise reasonable plan produces an unreasonable week. Alternatives the clinic lists include hyaluronic acid skin-hydration injectables, other polynucleotide products, microneedling, selected laser treatments, or topical skincare, depending on the concern being treated.

Safety, Precision, and Clinic Standards

Le.J Plastic Surgery is a Registered Medical Institution for Attracting Foreign Patients, certified by the Ministry of Health and Welfare in compliance with the Medical Overseas Expansion and Foreign Patients Attraction Act. This is a registration for treating international patients; it is not an accreditation of any treatment in this category.

The clinic's stated risk-reduction approach is appropriate patient assessment, checking allergies and medical history, using sterile injection techniques, and providing clear aftercare instructions.

For this treatment specifically, raise worsening pain, spreading redness, or other unusual symptoms with a clinician promptly rather than waiting for a scheduled follow-up. Le.J Plastic Surgery publishes neither case volumes nor complication rates for this procedure, and this page claims neither. That is a fair question at consultation, as is the one worth asking any surgeon in this category: how many of these operations they have performed, how many involved complications, and what follow-up to expect if something goes wrong.

A course rather than a single appointment is normal here, and that is a property of the treatment category rather than of this clinic: the American Society of Plastic Surgeons notes that minimally invasive or nonsurgical procedures may need more sessions or a combination of procedures to achieve desired results.

The Bottom Line

• Rejuran® delivers a polynucleotide material derived from purified salmon DNA by multiple small injections into selected areas of the skin.

• The targets are texture, hydration, elasticity and the appearance of fine lines — skin quality, not contour or volume.

• A session commonly takes approximately 20–40 minutes, and a course of sessions may be recommended.

• Improvement develops gradually over several weeks rather than appearing on the day.

• Temporary bumps, redness, swelling and bruising are common; infection, persistent inflammation and allergic reactions are the less common risks.

• The clinic publishes no protocol details, no outcome figures and no price for this service, and none are supplied here.

Frequently Asked Questions

What is actually being injected? A polynucleotide (PN) material derived from purified salmon DNA. It is a manufactured product rather than something taken from your own body, which is why the allergy and medical-history review before treatment is not a formality — known allergy to product ingredients is a stated reason the treatment may be unsuitable.

Will I see a difference straight away? No, and expecting one is the most common mismatch with this treatment. Improvements in skin hydration and texture may become noticeable over the following weeks, and the overall result depends on the number of sessions and individual response. What you will see on the day is the opposite — small injection-site bumps, redness or possible bruising.

How many sessions will I need? A course may be recommended, and the number depends on the product and your treatment goals rather than on a fixed protocol. This is a question to settle at consultation before booking travel, because the schedule, not the single appointment, determines how long you need.

Does it hurt, and what numbing is used? Rejuran involves multiple injections, so temporary stinging, pinching or discomfort is common, varying by individual and treatment area. Topical numbing cream is commonly used to help reduce discomfort during injections.

How long should I stay in Korea, and when can I fly home? A short stay is generally sufficient for an outpatient session, with extra time if a follow-up appointment is recommended or if bruising and swelling need assessment. You can generally fly once you feel comfortable and any immediate swelling or discomfort is manageable — confirm the timing with the treating clinic, especially if follow-up is planned.

Who should not have this treatment? People with known allergies to the product's ingredients or an active skin infection at the injection sites. Pregnancy, breastfeeding, bleeding disorders, certain medical conditions, and medications that affect bleeding all require medical review before treatment.

How do I prepare, and what should I avoid beforehand? Tell the clinic about your medical history, allergies, medications, supplements, previous injectable treatments, and any tendency to bruise. Avoid alcohol, and discuss blood-thinning medications or supplements with your clinician beforehand. Do not stop prescribed medication without medical advice, and postpone treatment if the skin is infected or significantly irritated.

How does this differ from the clinic's other skin injectables? By material and by target. Rejuran works through polynucleotides and is aimed at skin texture and quality; the clinic's other entries in this range use different materials and are weighted differently between skin quality and mild volume. Which is appropriate is a question for examination rather than preference, and the honest answer may be more than one of them in sequence.

Book a Consultation at Le.J Plastic Surgery

Rejuran® is offered at Le.J Plastic Surgery in Gangnam-gu, Seoul by Dr. Kim Ji Sun, within the clinic's Anti-Aging & Regenerative range. Because the result builds over weeks and may involve a course rather than a single appointment, the consultation is where the schedule as well as the treatment is decided. Consultations run Monday to Friday, 10:00–19:00 KST, and Saturday from 10:00 KST. International enquiries are handled by the clinic's counseling manager, Park Somi, and English-language support is available. You can use the clinic's contact page, by phone on +82-2-516-7153, or by email at info@lejplasticsurgery.com.

Disclaimer

This page is for general information only and is not medical advice. Individual results vary and cannot be guaranteed. Suitability for any procedure can only be determined through an in-person medical consultation with a qualified doctor.

Sources & Further Reading

• American Society of Plastic Surgeons — Minimally invasive procedures: What to know and where to start

• American Academy of Dermatology — Best questions to ask when considering a cosmetic treatment